Contraindicated (one)pentobarbital will minimize the extent or influence of cariprazine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. CYP3A4 is to blame for the development and elimination of cariprazine's Energetic metabolites.
pentobarbital will lessen the level or outcome of aripiprazole by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
pentobarbital will decrease the extent or result of etravirine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
buprenorphine transdermal and pentobarbital the two increase sedation. Prevent or Use Alternate Drug. Limit use to patients for whom choice therapy options are insufficient
pentobarbital will minimize the level or outcome of celecoxib by affecting hepatic enzyme CYP2C9/10 metabolism. Minor/Significance Unfamiliar.
pentobarbital will minimize the level or impact of nisoldipine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
pentobarbital will minimize the extent or outcome of maraviroc by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
pentobarbital will lower the extent or influence of fentanyl by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Intently. Coadministration of fentanyl with CYP3A4 inducers could lead on to some lower in fentanyl plasma concentrations, not enough efficacy or, maybe, enhancement of the withdrawal syndrome inside a individual who's got made Bodily dependence to fentanyl.
pentobarbital will lessen the extent or result of propafenone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Unidentified.
pentobarbital will minimize the extent or outcome of clozapine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
pentobarbital will lessen the level or influence of tramadol by here affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check. Lessened AUC of tramadol plus the active metabolite (O-desmethyltramadol) when coadministered with solid CYP3A4 and CYP2B6 inducers
pentobarbital will decrease the level or influence of alosetron by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Unfamiliar.
Contraindicated (one)pentobarbital will reduce the extent or effect of lonafarnib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Lonafarnib is often a sensitive CYP3A4 substrate. Coadministration with potent or reasonable CYP3A4 inducers is contraindicated.
Contraindicated (one)pentobarbital will minimize the extent or impact of lumefantrine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration with powerful CYP3A4 inducers may lead to decreased serum concentrations and lack of antimalarial efficacy